Eastern Panhandle Vacations from $156

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Your Eastern Panhandle Vacation

Leave the planning to us with an Eastern Panhandle vacation package. With everything arranged before you depart, the only thing you'll need to do is sit back, chill out and experience this destination's wonders to the fullest. With so much to explore on a trip to Eastern Panhandle, it can be difficult to know where to start. Kick off your journey in Winchester at Shenandoah Valley Discovery Museum and Dinosaur Land — two leading attractions here. Another city worthy of a spot on your itinerary is Martinsburg. Don't miss Martinsburg Mall and Chesapeake and Ohio Canal. Expedia is a one-stop shop for organizing your Eastern Panhandle vacation. From hotels and flights, to activities and more, we're here to help you curate a travel experience like no other.

The Latest Eastern Panhandle vacation packages

Price found within the past 48 hours. Click for updated prices.
Hotel Arboretum
Kellogg Conference Hotel at Gallaudet University
InterContinental Washington D.C. - The Wharf by IHG
DoubleTree by Hilton Hotel Laurel
The St. Gregory Hotel
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Where to stay in Eastern Panhandle

Find the best Eastern Panhandle areas and neighborhoods for the activities you enjoy most. Learn more about Eastern Panhandle

Discover the most popular places to visit in Eastern Panhandle

Eastern Panhandle Hotel Deals

Quality Inn

Quality Inn

2.5 out of 5
25 Union St, Harpers Ferry, WV
Fully refundableReserve now, pay when you stay
$81 nightly
The price is $90 total per night from Sep 7 to Sep 8
$90 total
Sep 7 - Sep 8
Total with taxes and fees
8.4/10 Very Good! (1,002 reviews)
"The location was convenient, easy parking in a safe area. The lobby area was neat and clean and the check in staff very helpful. The breakfast server Norma did an excellent job keeping the food available and the room clean. We struggled with internet connectivity throughout our stay while not a major ..."

Reviewed on Aug 21, 2025

Quality Inn
Holiday Inn Express Charles Town by IHG

Holiday Inn Express Charles Town by IHG

2.5 out of 5
681 Flowing Springs Rd, Charles Town, WV
Fully refundable
$107 nightly
The price is $121 total per night from Sep 1 to Sep 2
$121 total
Sep 1 - Sep 2
Total with taxes and fees
9.2/10 Wonderful! (1,004 reviews)
"Cheap, clean, and convenient"

Reviewed on Aug 21, 2025

Holiday Inn Express Charles Town by IHG
Dreamtime - Modern A-frame Cabin w/ Hot tub

Dreamtime - Modern A-frame Cabin w/ Hot tub

Berkeley Springs
$340 nightly
The price is $378 total per night from Sep 18 to Sep 19
$378 total
Sep 18 - Sep 19
Total with taxes and fees
10/10 Exceptional! (45 reviews)
"Cutest little house in the woods. We enjoyed the hot tub under the stars, and the very comfortable bed. It was quiet and relaxing in this home, and it was so nice to have the essentials provided (like coffee, sugar, creamer, garbage bags, paper towels, detergent). Very close to the brewery, and to ..."

Reviewed on Jul 16, 2025

Dreamtime - Modern A-frame Cabin w/ Hot tub
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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